Ozone Therapy

Ozone in medicine

In the last few years ozone is being investigated for applications in various medical fields. Medical ozone is always freshly prepared on site (in a special generator) for immediate administration. Standard ozone concentration for medical applications is determined by doctors. Applied concentrations ranges from 20 to 50 micrograms per milliliter. This type of ozone has different features include anti pain, Anti-inflammation, and regenerative (repair) effects. But here, we shall restrict our discussion in role of ozone in pain management. Ozone therapy is a unique form of therapy that both heals and detoxifies at the same time.

Ozone therapy applications

Ozone is used to treat a variety of problems include pain, inflammation, damage to tendons, joints or intervertebral discs of the lumbar or cervical. Mechanism of action is the reaction of free radicals in the molecule’s structure (ozone-third oxygen) with molecules in the disc, results in the decrease of inflammation, pain and shrinking down the disc herniation.
Moreover, ozone therapy is a useful treatment of arthritic knee, shoulder and other joints due to the destruction of articular cartilage and its inclusion in the joint space, resulting in inflammation, swelling and pain.
Reducing the pressure and weight on the joints, steroidal and non steroidal anti-inflammatory drugs, cortisone and hyalase injections are common treats used for arthritic joints. If the destruction of knee or shoulder joints are severe or patients age and health conditions is appropriate, replacement surgery may be recommended.
In cases where drug therapy is not effective and the patient is not candidate for surgery, injection of 10 milliliters of ozone gas is useful, which is used for anti-pain and anti-inflammatory effects that reduces inflammation and pain, and causes joint repair.


Despite the wonderful therapeutic effects, ozone is almost safe and non-toxic to human body. Hundreds of scientific and clinical studies has been investigated on the therapeutic effects of ozone. Ozone therapy has been in use by Dr. Bagheri, et al at Chamran University of medical sciences.
In recent years, more than 14000 patients with herniated lumbar disc have been treated by injecting ozone in Europe. In this method, under local anesthesia, ozone is injected into the disc. Most people who have undergone this treatment, have experienced pain relief after 48 hours.

Controlling chronic pain using modern and advanced interventional techniques

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